ABSTRACT
Background & objectives: Almost round-the-year occurrence of Salmonella Typhi and Salmonella Paratyphi A has been noticed in Rourkela since last 13 and five years respectively. The incidence of infection along with the antibiogram of these two serotypes in this area were carried out. Methods: The study was carried out at Ispat General Hospital, Rourkela, India, between January 2005 and December 2008 with 5340 blood samples collected from patients with suspected enteric fever and pyrexia of unknown origin. Isolation, identification and antibiogram of the causative organisms were performed according to standard bacteriological procedures. Results: A total of 298 Salmonella isolates showed an overall per cent positivity of 5.58. Multidrug resistance was found in 11.96 per cent and 15.62 per cent isolates of S. Typhi and S. Paratyphi A respectively. Less than 2 per cent isolates of Salmonella showed resistance to ciprofloxacin. A resistance of 3.0 to 6.25 per cent against third generation cephalosporins was observed among the salmonella isolates. Interpretation & conclusion: A round-the-year occurrence of Salmonella spp. in Rourkela might have been due to the presence of a considerable number of carriers in the locality, poor sanitation in nearby slum areas, and inadequate and contaminated community water supply at times. Higher degree of susceptibility among S. Typhi isolates against various antibiotics was encouraging, but increasing trend of resistance observed among S. Paratyphi A isolates was a matter of concern.
Subject(s)
Anti-Bacterial Agents/pharmacology , Cephalosporins/pharmacology , Ciprofloxacin/pharmacology , Community-Acquired Infections , Drug Resistance, Multiple/drug effects , Fever/drug therapy , Fever/epidemiology , Fever/microbiology , Humans , Incidence , India/epidemiology , Microbial Sensitivity Tests/methods , Paratyphoid Fever/drug therapy , Paratyphoid Fever/epidemiology , Paratyphoid Fever/microbiology , Salmonella paratyphi A/drug effects , Salmonella paratyphi A/isolation & purification , Salmonella paratyphi A/metabolism , Salmonella typhi/drug effects , Salmonella typhi/isolation & purification , Salmonella typhi/metabolism , Sanitation , Typhoid Fever/drug therapy , Typhoid Fever/epidemiology , Typhoid Fever/microbiology , Water PollutantsABSTRACT
Forty patients suffering from intractable unilateral trigeminal neuralgia involving more than one division of the trigeminal nerve were treated by percutaneous radiofrequency thermocoagulation of the trigeminal sensory root. The aim of the operation was to relieve the pain without producing dense sensory deficit in the face. This goal was achieved by making selective lesions in the sensory root with gradually increasing temperature 60 degrees C to 90 degrees C. Three to four consecutive lesions each for 60 seconds have been found to produce excellent pain relief in 77.7% with good and fair results in the rest. The recurrence rate has been found to be 15% during 2 years of follow-up. Considerable dysaesthesia was observed in 5% of cases. Corneal anaesthesia was found in 5% cases while one patient developed neuroparalytic keratitis. Transient trigeminal motor weakness was observed in 10% of patients.